ACS

November 2015 Meeting - Akron Section Award

(posted on Tuesday, November 10, 2015)

Dr. Adam Matzger

The 2015 Akron Section Awardee is Dr. Adam Matzger of the University of Michigan. On Nov. 17, Dr. Matzger will give an afternoon lecture at The University of Akron and an evening program at Hiram College. Dinner reservations are due by Nov 12.

The University of Akron - 111 Mary Gladwin Hall

 3:30 pm - Afternoon Lecture
       From Better Health to Improved Lethality: Controlling Crystallization of Pharmaceuticals and Explosives

Hiram College - Kennedy Center

5:30 pm - Networking
6:30 pm - Dinner ($25 for Professionals & Guests; $10 for Students)
7:30 pm - Evening Program
       Coordination Polymers: New Tricks for Old Dogs

 

The programs are free and open to the public. Dinner reservations are required by Nov. 12 - please contact Mike Davis (mdavis.nmr@gmail.com). A map of the Hiram College campus is below.

Biography - Adam Matzger

Adam Matzger received his B.A. degree in 1992 from Oberlin College. His Ph.D. was completed at the University of California at Berkeley in the group of K. Peter C. Vollhardt, where he conducted theoretical and experimental investigations of dehydrobenzoannulenes and phenylenes. He went on to postdoctoral work jointly with Nathan S. Lewis and Robert H. Grubbs at the California Institute of Technology investigating a novel class of chemical sensors. In 2000, he joined the faculty at the University of Michigan at Ann Arbor, where he is now the Charles G. Overberger Collegiate Professor of Chemistry and Professor of Macromolecular Science and Engineering. His current research interest focus is on organic materials in the solid state and encompasses crystalline polymorphs, explosive cocrystals, and porous materials.

Abstract - Afternoon Lecture
From Better Health to Improved Lethality: Controlling Crystallization of Pharmaceuticals and Explosives

The role of crystal packing in determining many of the important properties of solid materials has led to increased recognition of the phenomenon of polymorphism.  The ability of a solid to exist as more than one polymorph, supramolecular isomers that differ only in molecular packing, creates a situation where one crystal form may have great technological relevance while another has little value.  Examples of polymorphism in solid-state reactive compounds, nonlinear optical materials, and pharmaceuticals have been well documented.  Historically, scientists have not been able to control the formation of polymorphs in a general fashion.

Our approach to controlling crystal polymorphism involves creating synthetic polymer seeds to promote selective crystal growth.  Using polymers as heteronuclei offers rapid access to a diverse set of nucleation promoters with tunable properties.  Many of our initial studies have concentrated on controlling crystallization of pharmaceuticals because they have been extensively studied in connection with improving bioavailability.  Studies on polymorphic drugs have revealed the ability to exert significant control over their crystallization processes using insoluble polymers.  Recent discoveries will be described and alternative methods of controlling solid state properties will be discussed in the context of energetic materials.

Abstract - Evening Program
Coordination Polymers: New Tricks for Old Dogs

Adsorbents play a critical role in a variety of industrial, laboratory and consumer applications. Materials such as silica gel, zeolites, and activated carbon have been investigated for centuries and represent the most commonly used adsorbents. In the last decade research on new crystalline and high surface area materials based on coordination chemistry has accelerated. These materials are promising to redefine the types of processes and applications that can be enabled by adsorption. Synthetic challenges and novel approaches to the synthesis of microporous coordination polymers (MCPs) will be discussed. Recent progress in interfacing MCPs to polymers will be introduced as well applications in separations/storage of gases and air drying.

Hiram-campus-map Hiram-campus-map

 











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